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1.
PLoS One ; 19(1): e0295801, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38266011

RESUMO

The escalating prevalence of cybersecurity risks calls for a focused strategy in order to attain efficient resolutions. This study introduces a detection model that employs a tailored methodology integrating feature selection using SHAP values, a shallow learning algorithm called PV-DM, and machine learning classifiers like XGBOOST. The efficacy of our suggested methodology is highlighted by employing the NSL-KDD and UNSW-NB15 datasets. Our approach in the NSL-KDD dataset exhibits exceptional performance, with an accuracy of 98.92%, precision of 98.92%, recall of 95.44%, and an F1-score of 96.77%. Notably, this performance is achieved by utilizing only four characteristics, indicating the efficiency of our approach. The proposed methodology achieves an accuracy of 82.86%, precision of 84.07%, recall of 77.70%, and an F1-score of 80.20% in the UNSW-NB15 dataset, using only six features. Our research findings provide substantial evidence of the enhanced performance of the proposed model compared to a traditional deep-learning model across all performance metrics.


Assuntos
Algoritmos , Benchmarking , Segurança Computacional , Aprendizado de Máquina , Rememoração Mental
2.
Sci Rep ; 13(1): 5481, 2023 04 04.
Artigo em Inglês | MEDLINE | ID: mdl-37015978

RESUMO

The rapid spread of SARS-CoV-2 threatens global public health and impedes the operation of healthcare systems. Several studies have been conducted to confirm SARS-CoV-2 infection and examine its risk factors. To produce more effective treatment options and vaccines, it is still necessary to investigate biomarkers and immune responses in order to gain a deeper understanding of disease pathophysiology. This study aims to determine how cytokines influence the severity of SARS-CoV-2 infection. We measured the plasma levels of 48 cytokines in the blood of 87 participants in the COVID-19 study. Several Classifiers were trained and evaluated using Machine Learning and Deep Learning to complete missing data, generate synthetic data, and fill in any gaps. To examine the relationship between cytokine storm and COVID-19 severity in patients, the Shapley additive explanation (SHAP) and the LIME (Local Interpretable Model-agnostic Explanations) model were applied. Individuals with severe SARS-CoV-2 infection had elevated plasma levels of VEGF-A, MIP-1b, and IL-17. RANTES and TNF were associated with healthy individuals, whereas IL-27, IL-9, IL-12p40, and MCP-3 were associated with non-Severity. These findings suggest that these cytokines may promote the development of novel preventive and therapeutic pathways for disease management. In this study, the use of artificial intelligence is intended to support clinical diagnoses of patients to determine how each cytokine may be responsible for the severity of COVID-19, which could lead to the identification of several cytokines that could aid in treatment decision-making and vaccine development.


Assuntos
COVID-19 , Humanos , Inteligência Artificial , SARS-CoV-2 , Aprendizado de Máquina , Citocinas
3.
J Big Data ; 9(1): 5, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35013702

RESUMO

The purpose of this study is to develop and test machine learning-based models for COVID-19 severity prediction. COVID-19 test samples from 337 COVID-19 positive patients at Cheikh Zaid Hospital were grouped according to the severity of their illness. Ours is the first study to estimate illness severity by combining biological and non-biological data from patients with COVID-19. Moreover the use of ML for therapeutic purposes in Morocco is currently restricted, and ours is the first study to investigate the severity of COVID-19. When data analysis approaches were used to uncover patterns and essential characteristics in the data, C-reactive protein, platelets, and D-dimers were determined to be the most associated to COVID-19 severity prediction. In this research, many data reduction algorithms were used, and Machine Learning models were trained to predict the severity of sickness using patient data. A new feature engineering method based on topological data analysis called Uniform Manifold Approximation and Projection (UMAP) shown that it achieves better results. It has 100% accuracy, specificity, sensitivity, and ROC curve in conducting a prognostic prediction using different machine learning classifiers such as X_GBoost, AdaBoost, Random Forest, and ExtraTrees. The proposed approach aims to assist hospitals and medical facilities in determining who should be seen first and who has a higher priority for admission to the hospital.

4.
J Big Data ; 8(1): 161, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34956819

RESUMO

Over the past few decades, due to human activities, industrialization, and urbanization, air pollution has become a life-threatening factor in many countries around the world. Among air pollutants, Particulate Matter with a diameter of less than 2.5 µ m ( P M 2.5 ) is a serious health problem. It causes various illnesses such as respiratory tract and cardiovascular diseases. Hence, it is necessary to accurately predict the P M 2.5 concentrations in order to prevent the citizens from the dangerous impact of air pollution beforehand. The variation of P M 2.5 depends on a variety of factors, such as meteorology and the concentration of other pollutants in urban areas. In this paper, we implemented a deep learning solution to predict the hourly forecast of P M 2.5 concentration in Beijing, China, based on CNN-LSTM, with a spatial-temporal feature by combining historical data of pollutants, meteorological data, and P M 2.5 concentration in the adjacent stations. We examined the difference in performances among Deep learning algorithms such as LSTM, Bi-LSTM, GRU, Bi-GRU, CNN, and a hybrid CNN-LSTM model. Experimental results indicate that our method "hybrid CNN-LSTM multivariate" enables more accurate predictions than all the listed traditional models and performs better in predictive performance.

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